Geistlich Mucograft® is a collagen matrix designed specifically for soft-tissue regeneration in the oral cavity1. It is indicated for gaining keratinized tissue2,3,4 and for recession coverage5,6.
Geistlich Mucograft® provides an alternative to autologous soft-tissue grafts2,4,5,6. Painful harvesting of tissue is avoided, benefiting patients and clinicians alike.
Leading clinicians rely on Geistlich Mucograft®:
- No harvest-site morbidity2,3,5-7.
- Less pain compared with autologous grafts2,4.
- Reduced surgical chair-time compared with autologous grafts2-6.
- Natural soft-tissue colour and texture match5,8,9.
- Early vascularization and good soft-tissue ingrowth10,11.
- Good wound healing, also in open situations2.
- Easy handling2 and application in a dry state.
Geistlich Mucograft® consists of two structures: the compact structure provides stability while allowing open healing; the spongy structure supports blood clot stabilization and ingrowth of soft-tissue cells.
References:
1. Biocompatibility according to ISO 10993-1. Data on file, Geistlich Pharma AG, Wolhusen, Switzerland.
2. Sanz M, et al.: J Clin Periodontol 2009; 36(10): 868-76. (clinical study)
3. Konter U, et al.: Deutsche Zahnärztliche Zeitschrift 2010; 65: 723-30. (clinical study)
4. Lorenzo R, et al.: Clin Oral Impl Res 2012; 23(3): 316-24. (clinical study)
5. McGuire MK & Scheyer ET: J Periodontol 2010; 81(8): 1108-17. (clinical study)
6. Cardaropoli D, et al.: J Periodontol 2012; 83(3): 321-28. (clinical study)
7. Herford AS, et al.: J Oral Maxillofac Surg 2010; 68(7): 1463-70. (clinical study)
8. Thoma, D, et al.: J Clin Periodontol 2012; 39(2): 157-65. (clinical study)
9. Nevins M, et al.: Int J Periodontics Restorative Dent 2011; 31(4): 367-73. (clinical study)
10. Ghanaati S, et al.: Biomed Mater. 2011 Feb; 6(1): 015010. (pre-clinical study)
11. Rocchietta I, et al.: Int J Periodontics Restorative Dent. 2012; 32(1): e34-40. (pre-clinical study)
* Mucograft® (prototype) exhibited highly similar physical, mechanical and biological properties to the final product Geistlich Mucograft® differing only in the porcine collagen source used.